Klinefelter Syndrome Causes, Symptoms, Diagnosis and Treatment

What Is Klinefelter Syndrome?

Klinefelter syndrome is a genetic condition characterized by set of symptoms that result from two or more X chromosome in males.

Klinefelter syndrome adversely affects testicular growth, and this can result in smaller than normal testicles. This can lead to lower production of the sex hormone testosterone

Klinefelter syndrome often isn’t diagnosed until adulthood. Most men with Klinefelter syndrome produce little or no sperm.

Causes Of Klinefelter Syndrome:

Klinefelter syndrome occurs as a result of a random error that causes a male to be born with an extra sex chromosome.

The extra chromosome is retained because of anondisjunction event during paternal or maternal meiosis I (gametogenesis).
Another mechanism for retaining the extra chromosome is through a nondisjunction event duringmeiosis II in the egg.
Contrary to popular belief, Klinefelter is not an inherited condition.

An older mother is at a higher risk f giving birth to a baby boy with Klinefelter syndrome.

Symptoms Of Klinefelter Syndrome:

The following signs and symptoms are exhibited:

In babies:

Weak muscles
Slow motor development — taking longer than average to sit up, crawl and walk
Delay in speaking
Quiet, docile personality
Problems at birth, such as testicles that haven’t descended into the scrotum

In boys and teenagers:

Taller than average stature
Longer legs, shorter torso and broader hips compared with other boys
Absent, delayed or incomplete puberty
After puberty, less muscular bodies and less facial and body hair compared with other teens
Small, firm testicles
Small penis
Enlarged breast tissue (gynecomastia)
Weak bones
Low energy levels
Shyness
Difficulty expressing feelings or socializing
Problems with reading, writing, spelling or math
Attention problems