Stevens-Johnson Syndrome Causes, Symptoms, Diagnosis and Treatment

Stevens-Johnson Syndrome

What Is Stevens-Johnson Syndrome?

Stevens-Johnson syndrome is a life threatening skin condition. It is a form of toxic epidermal necrolysis. In this syndrome, cell death causes the separation of epidermis from the dermis.
It is thought to be a hypersensitivity (a set of undesirable reaction brought about by normal immune system) complex which affects skin and mucous membranes.
Causes range from taking certain medications to infections. It is usually an overreaction of the immune system to a seemingly mild infection. This leads to exhibition of blisters and peeling of the skin.
What begins as symptoms for infection invigorates into red painful rash. The top affected layer of the skin then dies and sheds away.
Prompt treatment is integral in preventing organs from attaining any lasting damage. Treatment focuses on culminating the underlying cause, relieving symptoms and minimizing complications.

Causes Of Stevens-Johnson Syndrome:

Stevens-Johnson syndrome arises due to the hyperactivity of the immune system.

Possible causes, which may trigger the immune system to overreact include:

  •     Medications
    Vancomycin
    Allopurinol
    Valproate
    Levofloxacin
    Diclofenac
    Etravirine
    Isotretinoin
    Fluconazole
    Valdecoxib
    Sitagliptin
    Oseltamivir
    Penicillins
    Barbiturate
    Sulfonamides
    Phenytoin
    Azithromycin
    Oxcarbazepine
    Zonisamide
    Modafinil
    Lamotrigine
    Nevirapine
    Pyrimethamine
    Ibuprofen
    Ethosuximide
    Carbamazepine
    Bupropion
    Telaprevir
    Nystatin
    Radiation therapy
  •     Infections
    Upper respiratory infections
    Otitis media
    Pharyngitis
    Epstein-Barr virus
    Cytomegalovirus infections.
    Diphtheria
    Brucellosis
    lymphogranuloma venereum
    Mycobacteria
    Tularemia
    Typhoid
    Herpes
    HIV
    Hepatitis
    Pneumonia

Symptoms Of Stevens-Johnson Syndrome:

The following symptoms may be exhibited by affected individual:

  •     Facial swelling
  •     Tongue swelling
  •     Hives
  •     Skin pain
  •     A red or purple skin rash that spreads within hours to days
  •     Blisters on skin and the mucous membranes of mouth, nose, Eyes and genitals
  •     Shedding of skin
  •     Fever
  •     Sore mouth and throat
  •     Fatigue
  •     Cough
  •     Burning eyes

Diagnosis Of Stevens-Johnson Syndrome:

Stevens-Johnson syndrome can be diagnosed via:

  •     Medical history
  •     Physical exam
  •     Skin test

Treatment Of Stevens-Johnson Syndrome:

The following treatment options are available:

  •     Medications
    To control infections
    To relieve itching and painful rash
    To reduce discomfort
  •     Supportive care
    Eye care
    Fluid replacement, since skin loss results in loss of fluids]Wound care, for blisters

By : Natural Health News

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